Curriculum vitae

Name Wolfgang Holzgreve, MD, MS, FACOG, FRCOG, MBA, Professor  of Obstetrics and Gynecology Medical Director and CEO University Medical Center Bonn
Date of Birth 15. Oktober 1955, Möhnesee-Körbecke (Westfalia), Germany
Marital Status Married, two children

Adress

Work: Sigmund-Freud-Strasse 25
D-53127 Bonn
wolfgang.holzgreve@ukbonn.de
Privat: Schaumburg-Lippe-Strasse 4c
D-53113 Bonn
wolfgang@holzgreve.net

Training

Secondary education
1966-1973 Staatl. Archigymnasium Soest Germany (classical languages, skipped one class, prize for best graduation).
Graduation
1973–1975 Premed, University of  Münster, Germany (Member of the Study Foundation of the German People)
1976 Master of Science in Health and Medical Sciences, School of Public Health, University of California, Berkeley, USA
1976-1978 Medical School, University of Münster, Germany
1978-1979 Internship in Obstetrics and Gynecology, Bethesda Hospital, Bielefeld-Bethel, Germany
1979 Doctoral dissertation “summa cum laude”
1979-1982 Residency in Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University of Münster, Germany
Postgraduate
1982-1984 Postdoctoral Fellowship of the German Research Foundation in Reproductive Genetics at the University of California, San Francisco, USA
 1984-1985 Specialization in Obstetrics and Gynecology, Department of Obstetrics and Gynecology, University of Münster, Germany, Board Certification in Obstetrics and Gynecology, in Clinical Genetics and in Sports Medicine
2007 Master of Business Administration (MBA), Lasalle University, Philadelphia, USA

Akademic Appointments

1986 Privatdozent (Assistant Professor) at the Department of Obstetrics and Gynecology, University of Münster
1987 Tenure position at the Department of Obstetrics and Gynecology, University of Münster
1991-1995 Professor of Obstetrics and Gynecology, University of Münster
1995-2008 Chairman of the Department and Chief of Service, Department of Obstetrics and Gynecology University of Basel, Switzerland
2008-2010 Medical Director and Chairman of the Board of Directors of the University Medical Center Freiburg
Okt. 2010 Sabbatical at the Wissenschaftskolleg/Institute of Advanced Study Berlin, Fellow with Research on “Capacity -2011 Building to improve Mother and Child Health Care in Low Income Countries
Jan. 2012 Medical Director and CEO, Universitäty Hospital Bonn

Publications
621 articles in scientific journals (incl. New England Journal of Medicine, Journal of the American Medical Association, Lancet, American Journal of Obstetrics and Gynecology, Obstetrics and Gynecology, Prenatal Diagnosis, American Journal of Medical Genetics, American Journal of Reproductive Immunology, Mol. Hum. Reprod., Nucleic Acid Res., Clin Chemistry); 168 articles in non peer-reviewed journals; 256 book chapters and 13 books, 1025 abstracts at scientific meetings, 669 oral presentations at postgraduate courses. Hirsch-Index (h-index): 41 (Upper 1% in Medicine), According to Research ID: F-7884-210, case : TS-00329439, ref. 00D3 un.5007E9XXZ, 2010: 6611 sum of times cited, 583 papers (323 obstetrics and gynecology, 91 genetics and heredity, 53 pediatrics, 46 reproductive biology, 38 medicine, general and internal medicine)

Editorial Board Member (Past or Present)
Molecular Human Reproduction; Ultraschall in Klinik und Praxis; PerinatalMedizin; Prenatal Diagnosis; Anatolian Journal of Gynecology and Obstetrics; Journal of Hellenic Society for Ultrasound in Medicine and Biology; Gynäkologische Praxis; Ultrasound Quarterly; Zentralblatt für Gynäkologie; Fertilität; Expert Review of Molecular Diagnostics; American Journal of Medical Genetics; Ultrasound in Obstetrics and Gynaecology; Ultrasound Review; Molecular Human Reproduction; Expert Review in Molecular Medicine; Prenatal and Neonatal Medicine; Journal of Perinatal Medicine; European Medical Journal Reproductive Health, Hypertension in Pregnancy, International Journal of Person Centered Medicine, International Journal of Ultrasound in Obstetrics and Gynecology (Associate Editor), Chimerism, Andrology Gynaecology, Case Reports in Perinatal Medicine, Pregnancy Hypertension- Int. Journal of Women´s Cardiovascular Health, Menopause Review, European Medical Journal – Gynecology and Obstetrics, International Journal of Person-Centred Medicine (in Collaboration with WHO).

Editor (Past or Present)

Fetal Diagnosis and Therapy; Zeitschrift für Geburtshilfe und Neonatologie; Reproduktionsmedizin; Therapeutische Umschau; American Journal of Obstetrics and Gynecology (International Editor), Chimerism, International Journal of Women´s Cardiovascular Health.

Grants
NIH (USA) for „Non invasive prenatal diagnosis“ 1,8 Mio US$, Deutsche Forschungsgemeinschaft (German Research Foundation), Schweizerischer Nationalfonds (Swiss Science Foundation). 4 projects of the EU

Patents
Echogenic CVS Aspiration Catheter (Angiomed, Germany) „Non-invasive procedure for prenatal diagnosis of genetic anomalies“ (Patent No. 0597068) European Patent No. 01811266.4: “Human Mitochondrial DNA Nucleotides as Genetic Markers in Transfusion Medicine” European Patent No. 02405033.8: “Method for the Diagnosis of Chromosomal and/or Genetic Abnormalities”

Prizes / Honors (Selection)

1986 Prize of the European Association of Perinatal Medicine
Bi-Annual Prize of the German Society of Gynecology and Obstetrics
1989 Annual Prize of the Drs. Haackert-Foundation for the Advancement of Prenatal Medicine
1993 Prize of the German Society for Perinatal Medicine “Maternité”
1994 Aw Boon Haw Visiting Professor University of Hong Kong
1995 Research Prize of the Werner G. Gehring Foundation
2000 Honorary Professor at the Yonsei Medical Research Center, Yonsei University College of Medicine
Election as Member of the National German Academy of Sciences Leopoldina
2001 Liley Medal of the International Society “Fetus as a Patient
2002 Honorary Membership of the Associación Bogotana de Perinatologica, Columbia
2004 Kyank Lecture Rostock University
Fellow ad eundem of the Royal College of Obstetricians and Gynaecologists
2005 Corresponding member of the Austrian Society of Perinatal Medicine
Francis Crick Medal at the Inaugural Meeting of the International Academy of Perinatal Medicine
Erich Saling Prize of the World Association of Perinatal Medicine
2006 Honorary Member of the American College of Obstetrics and Gynecology
2007 Charter Day Lecture National Maternity Hospital Dublin
Honorary Fellow of the American Gynecological and Obstetrical Society (AGOS), Joseph Price Oration
2008 Haackert Gold Medal for Lifetime Achievements in Prenatal Medicine

Gold Medal of Charles University Prag

Honorary Member, Westfalian Society of Gynecology and Obstetrics

2010 5th Honorary Doctor degree
2011 Honorary member of the Polish Society of Obstetrics and Gynecology
2012 Honorary member of the Nigerian Society of Obstetrics and Gynecology
2014 Health Media award for Innovative Communication at the University of Bonn Medical Center
2016 Honorary member of the Ukraine Society of Obstetrics and Gynecology

Memberships / Presidencies of Scientific and Medical Associations (Selection of Past and Present)
Society for Gynecologic Investigation (SGI); Society for Perinatal Obstetricians, now SMFM; German Society of Gynecology and Obstetrics (Board Member); German Society of Perinatal Medicine (President); German Society of Ultrasound in Medicine and Biology (Level III-Board); Swiss Association of Chairs in Departments of Obstetrics and Gynecology (President); European Society of Perinatal Medicine (Board Member); International Society „The Fetus as a Patient“ (Vice-President); German Society of Reproductive Medicine (President); World Federation of Perinatal Medicine (Chairman, Scientific Committee); Ethics Boards of the Novartis Co. and the Swiss Bishops’ Conference; Scientific Board on „Multivitamins in Pregnancy” of Roche/Bayer and BayerSchering Consumer Health (Chairman); International Academy of Human Reproduction; International Academy of Perinatal Medicine (Founding Member); Member of the Regenz (Senate) of the University of Basel; Member of the Spitalleitung (Hospital Board) of the University Hospital Basel; World Association of Medical Editors; Trinational Upper-Rhine Society of Obstetrics and Gynecology (Board Member); European Board and College of Obstetrics and Gynecology (EBCOG) (Secretary General / Treasurer); Publications Management Board of FIGO (Chair); Accredited Representative of the International Federation of Gynecology and Obstetrics (FIGO) to the UN and WHO in Geneva; Officer of the International Federation of Gynecology and Obstetrics (FIGO) for 6 years

Positions Offered (Not Accepted) Since 1990
Division Chief Northwestern University Stanford University, Chicago, University of Utah, Salt Lake City, University of Pittsburgh, University of California San Francisco, Professor and Chairmanship, St. Louis University, St. Louis, USA, Professor of the Department of Obstetrics & Gynecology, University of Manchester, UK (Chairmanship), C4 Professur für Geburtshilfe und Perinatologie MHH Medical University of Hannover, Germany (Chairmanship), C4 Professur für Geburtshilfe und Gynäkologie, University of Münster Germany (Chairmanship), C4 Professur für Geburtshilfe und Gynäkologie University of Munich, Germany (Chairmanship)

Achievements in Hospital Management
Basel (1995-2008): Increase of University Women’s Hospital market share from 42 to 76%, deliveries from 1400 to >2000, operations from 2500 to >3000; 30 000 outpatient consultations; move to new women’s hospital building and political approval for building of new pediatric hospital (opening 2010) Freiburg (2008-2010): Preparation of Merger with Cardic Center Bad Krozingen (ca. 1000 employees); merger of two breast centers and preparation for acquisition of private hospital (KTB) by the University of Freiburg Medical Center Bonn (2012-today): Concentration of the buildings and activities in one campus for improvement of processes, medical quality and economic health 2017: Achievement of number one position in the State of Northrine-Westfalia /7 University Hospitals) in number one Position of the Magazine Focus for the fifth time in a row 2015

Other Activities (Selection)

1998 WHO-Consultant on Prenatal Diagnosis of Sickle Cell Anemia and Beta-thalassemia, Field work in Nigeria
1999 Founding and Board Member of the “Swisscord Association for the support of stem cell transplantations from cord blood
Co-Organizer of the Symposium “Molecular Medicine of the “Swiss Academy of Medical Sciences
Organizer of the “Ernst Schering Research Foundation Workshop on “Stem Cells from Cord blood, in Utero Stem Cell
Development and Transplantation inclusive Gene Therapy , Berlin
2000 FIGO Expert Advisory Panel on Prenatal and Preimplantation Genetics, Diagnosis and Therapy
Invited collaborator on the “Encyclopedia of the Human Genome of the Nature Publishing Group (Co-author of the
chapter on Fetal diagnosis)
Collaborator in the EU project “Eurograpp : Provision of genetic services in Europe
Invited participant and lecturer at the NICHD conference on “Biological implications of bidirectional fetomaternal Cell
trafficking , Detroit, 7/2000
Contract in the EU project “European Network for Fetal Transplantation (ENFET)
2001 Start of the Project NFP46 of the Swiss National Science Foundation on “In utero transplantation of hematopoetic
stem cells for definitive treatment or tolerance induction in recipients affected by genetic diseases
President of the Scientific Committee of the 5th World Congress on Perinatal Medicine
Marrow Transplantation , Montreux, 3/2002
2002 Chair of the session “In utero transplantation at the 28th Annual Meeting of the European Group for Blood and
Marrow Transplantation , Montreux, 3/2002
Chair of the plenary session “Genetic and molecular diagnosis and treatment at the XVIIIth European Congress on
Perinatal Medicine, Oslo, 6/2002

President of the jury for the Schering Prize for the Swiss Society of Obstetrics and Gynecology

President of the 26th Tree Country Annual Meeting of the German-speaking Societies for Ultrasound in Medicine

Reviewer of the Stem Cell Network North Rhine Westphalia, Düsseldorf, 11/2002
Board-Member of the Renner-Foundation for Families with Cancer-victims
2003 Invited participant and moderator of the NIH conference “Sharpening the tools. Current status and future directions
for the use of fetal cells and DNA from maternal blood for prenatal diagnosis , Bethesda, 1/2003
Moderator and co-organizer of the conference “Research on Human Embryos: Terra Incognita of the Swiss
Academy of Medical Sciences, 3/2003
Co-organizer of the conference “The Future of Transplantation of Cells, Tissues and Organs. Medicine, Ethics, Law
of the NFP Project 46 together with the Swiss Academy of Medical Sciences and the German Academy Leopoldina,
Monte Verita, Ascona, 9/2003
Advisor of the EU Network of the Excellence project “SAFE: Special Advances in Fetal Evaluation Network
Collaborator in the project “Quality management of stem cell transplantations (JACIE) , Basel
Medicine, Berlin, 11/2003
Collaboration in the Publiforum “Research on Humans of the Center for the Assessment of Research at the Swiss
Science and Technology Council
Co-author of the position paper on “The Use of Stem Cells. View of the European Board and College of Obstetrics and Gynecology , published in the European Journal of Obstetrics, Gynaecology and Reproductive Sciences
2004 Lecturer and Discussant in the Session “Dialogue on Ethical Questions related to Embryonic Human Stem Cell Research at the World Economic Forum, Davos, 1/2004
Ad hoc consultant for Epigenomics Inc. in Seattle
Counseling of the Vita 34 Company on Autologous Cord Blood Banking
On invitation of Prof, Huber, Rektor of the University of Munich, and Prof. Winacker, DFG president, reviewer of the
“New Concept of the Gene Center at the University of Munich
Member of the Committee for the new University Pediatric Hospital of two cantons in Basel
Organizer as President of the Swiss Society for Obstetrics and Gynecology for the 50 Year Anniversary of FIGO, Geneva, 7/2004
2005 Presentation of the keynote lecture on “Fetal-Maternal interactions as the Erich Saling Prize recipient at the 7th World of Perinatal Medicine
Member of the Review Team for the German Research Foundation Program on “Mechanisms of embryo-maternal communication , München 9/2005
2006 Representative of the Swiss Society of Obstetrics and Gynecology for the (National) Journal of the Swiss Association of Medicine (FMH)
Price Oration at the American Obstetrical and Gynecological Society (AGOS) meeting
Member of the Editorial Board of the Swiss Web-based E-learning Platform for Obstetrics and Gynecology (EGONE)
Member of the Advisory Board of Swissmom, Pregnancy Counseling Website Web Site of Switzerland
2007 Consultant to the Sultanate of Oman Ministry of Health on “Establishing Molecular Tests for Genetic Blood Disorders
Participant in the EU-grant Nanocel-Analysis of tumor cells and DNA in the circulation
Prize together with X.Y. Zhong of the JGO for contributions to Non-invasive Prenatal Diagnosis
Council of the Swiss Teratogen Infermation Service (STIS) in Lausanne (CHUV)
2008 Matres mundi International Advisory Council
Local Organizing Committee, 19th World Congress of Ultrasound in Obstetrics and Gynecology, Hamburg
2009 Invited lecturer at Health Management conferences in Berlin, Münster, Bonn and Quebec
FIGO representative at the meeting “Role of WHO in Diagnostic Imaging” , Geneva
2010 FIGO representative and speaker at the Third Geneva Conference on Person-centered Medicine Participation as Member of the German National Academy of Science Leopoldina Delegation in the G8+5 Meeting in Ottawa, Canada
Scientific Advisory Board of Sequenom, San Diego, USA
Organizing Committee for the Congress of the Society for the Study of Hypertension in Pregnancy (ISSHP) Int. Meeting to be held in Geneva 2012
Delegate of FIGO in the Guideline Scoping Meeting on “WHO Recommendations to optimize health woker roles to improve maternal and newborn health , Geneva, Dec., 2010
Participation as FIGO Officer in the Annual Review Meeting of the FIGO-Bill and Melinda Gates Foundation Program on “Improving maternal and newborn health in low-resource countries through strengthening the role of obstetric and gynecological national associations , Addis Abeba, October, 2010
Chair of the Global Scientific Advisory Board for the Development and Implementation of Folate Containing Oral Contraceptives to Prevent Neural Tube Defects and other Malformations, Result achieved at the end of 2011: First OC plus OC now approved by the Food and Drug Administration (FDA) but not yet by the European Medicines Agency (EMA)
Field work in Eritrea with the German NGO Archemed and government support in the program to improve mother/child health and to build up training curricula at the University and in the periphery, Training of skilled birth attendants and at the same time building and expanding of hospital services in the capital Asmara and now Keren, Result: Significant success with capacity building and increasing motivation of population to go to the health care facilities, excellent response to advocacy efforts at government and other levels regarding women s rights
2011 Election into the Editorial Boards of the “International Journal of Person Centered Medicine associated with the World Health Organization, the World Medical Association, the International Federation of Gynecology and Obstetrics, the International Council of Nurses, the International Federation of Medical Students Associations, the International Alliance of Patients Organizations and and 13 more international health institutions which adhere to this perspective and co-sponsered the Geneva Conferences on Person-Centered Medicine 2008, 2009, 2010 and 2011
Co-Chair of the Focus Group “Aging and Fertility of the German National Academy of Sciences “Leopoldina and Member of the Focus Group “Health
Representative for “Obstetrics/ Gynecology” of the National Academy of Sciences Leopoldina for the Science Year 2011 “Research for our Health
Member of the Research and Innovation Committee of the US-American Maternal Fetal Medicine Foundation/Nuchal Translucency Quality Review Program
       

 

Scientific Advisory Board of the Foundation “Deutsche Stiftung” Leben schenken and Member of the Jury of the Annual Innovation Prize for Research in the area of stem cells/ cord blood of this Organization awarded in Hannover, January 2011
2012 Activities in the German Charity organization Archemed which helps the State of Eritrea in the area of Maternal-Fetal Medicine
2013 Expert in CHAIN Network of the “NHS Research &
Development Programme of the United Kingdom”
2014 Chairman at Hohenkammer Castle of the Strategy Circle Conference of Managers of Health Care Centers in Germany Member of the Board University Club Bonn Co-Operation in the Project “Governance of Hospital Networks: Lessons from Hospital and non-Hospital alliances (chairs: Pierre Collerette and Michael Meberer, University Basel)   Chair of the Plenary Symposium: Public health and people-centered integrated care for all. WHO- Congress, Geneva,     April 28-30, 2014
2015        Chair of the Symposium: Healthy Aging today – Scientific achievements and practical consequences. Former German Paliamentary Building, Bonn, Oct. 17, 2015 Chair of the Symposium: How can we balance suffering from waste in high resourced countries and suffering from needs in low resourced countries? Clara Angela Foundation, Berlin, December 4, 2015 Moderator of the Symposium “Health risks and crisis interventins in Africa. “International University Forum”, Mach 3, 2015 Co-Präsident des 16th World Congress on human Reproduction, Berlin March, 18- 21, 2015 Otto Kaiser Memorial lecture on “Progress in Prenatal Medicine”, Basel August, 27, 2015 Chair of the Symposium: “Innovations in Genetics”, COGI-Congress, Frankfurt, May 14-15, 2015 Scientific Advisory Board, March of Dimes Foundation
2016 Member of the Board, Rehabilitation Center “´Godeshöhe”  Member of the Scientific Advisory Board Sequenzen, San Diego
Member of the Quality Assurance Committe, Association of German University Hospitals VUD
2017 Board Member of the German Foundation “Women´s Health”